Which historical event is depicted in the painting "Embarkation of the Pilgrims"?

The painting "Embarkation of the Pilgrims" depicts a significant moment in American history: the departure of the Pilgrims from Europe to the New World. This work illustrates the moment when these early settlers prepared to leave for America, seeking religious freedom and new opportunities, which were central themes in their journey. The emphasis of the artwork is on their resolve and hope as they set sail, capturing the essence of their voyage across the Atlantic Ocean to found a new life.

The other events mentioned do not align with the specific focus of the painting. The signing of the Declaration of Independence occurred much later in American history and does not relate to the Pilgrims' journey. The first Thanksgiving was a celebration that happened after the Pilgrims had already settled in America, while the establishment of Jamestown relates to a different group of settlers and a distinct event in colonial history. Therefore, the correct answer stands as the depiction of the Pilgrims' voyage to America.